Feb 15, 2011

METHOTREXATE AND SIDE EFFECTS



Methotrexate is a class of drugs called antimetabolites. Cancer treated with methotrexate slowed the growth of cancer cells. Methotrexate psoriasis by slowing the growth of skin cells to form scale to stop. Methotrexate to treat rheumatoid arthritis may be that the immune system activity. Methotrexate is used to treat psoriasis, an inflammatory disease of the skin, and arthritis which occurs in 10 percent of these patients (psoriatic arthritis). Methotrexate has been used to induce patients who had a miscarriage ectopic pregnancy. Your doctor will tell you how many times you have to methotrexate. If you are taking methotrexate for the treatment for psoriasis or rheumatoid arthritis, your doctor may tell you the medicine once a week. Pay special attention to the instructions of your doctor. Methotrexate Take exactly as directed. If you are taking methotrexate for the treatment for psoriasis or rheumatoid arthritis, your doctor may start with a low dose of medication and gradually increase the dose. Continue to take methotrexate, even if you feel comfortable. Do not stop taking Methotrexate without checking with your doctor. Tell your doctor or pharmacist if you are allergic to methotrexate or methotrexate, other medications, or any of the excipients in tablets. if you want including dental surgery, tell your doctor or dentist that you are taking methotrexate.

Methotrexate can be taken with or without food. In rheumatoid arthritis and psoriasis, the dose of methotrexate was administered weekly by injection or orally. The use of non-steroidal anti-inflammatory drugs (NSAIDs) before or during treatment with methotrexate can cause serious side effects, because NSAIDs may increase blood levels of methotrexate. The combination of methotrexate with drugs that can affect the liver or kidney or liver additional renal toxicity. Methotrexate can cause itching, rashes, dizziness and hair loss.

Methotrexate in rheumatoid arthritis
In 1940, methotrexate has been developed to treat leukemia. It was in 1970, methotrexate, an experimental treatment for rheumatoid arthritis, there is now a drug approved by FDA. First, methotrexate in patients who have not responded to other treatments not prescribed. Patients were then prescribed methotrexate when nonsteroidal anti-inflammatory drugs (NSAIDs) or other disease-modifying antirheumatic drugs (DMARDs), such as helped: Methotrexate is currently the standard treatment for patients with rheumatoid arthritis pain with stiffness moderate to severe swelling and fatigue.

Methotrexate is an antimetabolite. Methotrexate is a powerful medication, and many feared for their potential toxicity and questioned its safety. Methotrexate is a long-term treatment.

Side Effects
The most common side effect of methotrexate is nausea. Methotrexate is a chemotherapeutic agent that is mainly used to treat the following types of cancer. Side effects associated with methotrexate, can vary from person to person. In some patients, severe side effects, while others may experience only minimal side effects. Since white blood cells to fight the major types of cells, infection, low white blood cells can fight on your ability to infection. When low on the other hand, if the WBC is with fever (febrile neutropenia and called a low number of white blood cells), many times, will be hospitalized for intravenous antibiotic treatment. Reduction of red blood cells, called anemia. Usually one, your doctor blood checked weekly to monitor your blood, but if the numbers lower than blood, your doctor may ask more often the blood of the balance
Methotrexate can darken the skin. Fatigue and tiredness. Methotrexate can fatigue and exhaustion. Methotrexate may cause nausea and vomiting in some patients, but there are very effective drugs that can help prevent or greatly reduce nausea and vomiting. Hair loss is relatively rare, with small doses of methotrexate. However, higher doses of methotrexate can cause significant loss of hair. Methotrexate, the normal function of the liver due to disturbing abnormal liver tests. Methotrexate may be an allergic reaction in the form of a rash. Treatment of high-dose methotrexate may neurological problems such as headaches difficulties, speech difficulties, behavioral problems and seizures.

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